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Statistical analysis Sample size calculation indicated that at least 160 participants were required in each group for 80% power at an alpha level of 5% for Type I error to detect a 15% statistical difference between study groups (control group and genetic group, proportions p 1 =0.30 and p 2 =0.45, respectively)

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An evidence base needs to be built before products like Juul can be determined clinically sound or not sound, he said

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